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. 2017 Jun 14;12(6):e0179160. doi: 10.1371/journal.pone.0179160

Table 2. Characteristics of influenza A(H3N2) cases and test negative controls in Spain, seasons 2011–2012, 2013–2014 and 2014–2015.

Influenza season 2011–2012 2013–2014 2014–2015
Controls Cases Controls Cases Controls Cases
N (%) N (%) p N (%) N (%) p N (%) N (%) p
Total 430 (100) 674 (100) 440 (100) 322 (100) 358 (100) 362 (100)
Age groups (years) .016 .876 .003
    9–14 53 (12) 83 (12) 50 (11) 32 (10) 56 (16) 84 (23)
    15–44 223 (52) 301 (45) 220 (50) 159 (49) 160 (45) 158 (44)
    45–64 116 (27) 191 (28) 120 (27) 90 (28) 110 (31) 76 (21)
    ≥65 38 (9) 99 (15) 50 (11) 41 (13) 32 (9) 44 (12)
Sex .788 .542 .374
    Male 209 (49) 322 (48) 217 (49) 166 (52) 178 (50) 168 (46)
    Female 221 (51) 352 (52) 223 (51) 156 (48) 180 (50) 194 (54)
Target groups .023 .817 .866
    No 320 (75) 461 (68) 300 (68) 217 (67) 267 (75) 268 (74)
    Yes 108 (25) 213 (32) 140 (32) 105 (33) 91 (25) 94 (26)
Major chronic conditions .836 .421 .981
    No 365 (85) 569 (84) 343 (78) 243 (75) 291 (81) 294 (81)
    Yes 65 (15) 105 (16) 97 (22) 79 (25) 67 (19) 68 (19)
Previous influenza vaccine .805 .706 .208
    No 374 (87) 581 (86) 380 (86) 275 (85) 324 (91) 317 (88)
    Yes 56 (13) 91 (14) 60 (14) 47 (15) 34 (9) 45 (12)
Current influenza vaccine .517 .424 .531
    No 371 (86) 572 (85) 382 (87) 273 (85) 317 (89) 315 (87)
    Yes 59 (14) 102 (15) 58 (13) 49 (159 41 (11) 47 (13)
Onset-swabbing ≤ 4days .062 .697 .197
    No 18 (4) 15 (2) 10 (2) 6 (2) 7 (2) 3 (1)
    Yes 412 (96) 659 (98) 430 (98) 316 (98) 351 (98) 359 (99)