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. 2017 Jun 14;12(6):e0179387. doi: 10.1371/journal.pone.0179387

Table 3. Trends in the incidence and mortality of thyroid cancer and in the incidence of thyroidectomy, 1998–2012; Switzerland.

All rates are directly standardized on the European population. CI: confidence interval.

Women Men
Absolute annual mean change in rate [per 100’000] 95% CI [per 100’000] Relative increase per year 95% CI [%] Absolute annual mean change in rate [per 100’000] 95% CI [per 100’000] Relative increase per year 95% CI [%]
Incidence + 0.43 0.37 to 0.49 + 7% 6% to 8% + 0.11 0.07 to 0.15 + 4% 3% to 6%
Incidence by histologic typea
Papillary + 0.41 0.35 to 0.47 + 10% 9% to 12% + 0.11 0.08 to 0.15 + 8% 6% to 11%
Non-papillary + 0.02 0.00 to 0.04 + 1% 0% to 2% 0.00 -0.03 to 0.02 - 1% - 2% to 2%
Other/unknown + 0.01 -0.01 to 0.02 0% - 2% to 7% + 0.01 0.00 to 0.02 + 17% - 9% to 44%
Incidence by stageb
Early + 0.47 0.32 to 0.62 + 9% 6% to 12% + 0.11 0.04 to 0.19 + 7% 3% to 13%
Advanced + 0.02 -0.03 to 0.06 + 1% - 2 to 4% + 0.05 0.02 to 0.09 + 6% 2% to 11%
Unknown 0.00 0.00 to 0.01 0% - 0.00 0.00 to 0.00 0% -
Mortalitya - 0.02 -0.03 to -0.01 - 3% - 4% to - 2% - 0.01 -0.02 to 0.00 - 2% - 4% to - 2%
Surgery incidencec
Thyroidectomy + 0.59 0.53 to 0.64 + 17% 16% to 19% + 0.20 0.17 to 0.23 + 15% 13% to 17%

Data sources:

aNational Institute of Cancer Epidemiology and Registration (NICER);

bNICER limited to 5 regions (cf. Methods section);

cSwiss Federal Statistical Office (SFSO), Hospital Medical Statistic