Figure 4.
(a) The prevalence (%) of coexistence of anxiety and depression symptoms using HSCL-25 cutoff ≥1.75 at ages 31 and 46 in control (Ctrl) women and in women with OA, H, or PCOS. At age 31, the prevalence of coexistence was higher in H and PCOS groups. At age 46, only in the H group was the coexistence higher than in the controls, although a similar trend was also shown in the PCOS group (**P < 0.01, ***P < 0.001). (b) The risk [OR (95% CI)] for coexistence of HSCL-25 anxiety and depression using cutoff ≥1.75 in the OA, H, and PCOS groups. At age 31, the risk was higher in H [OR: 2.12 (1.40 to 3.21)] and PCOS groups [OR: 2.43 (1.34 to 4.39)]. At age 46, only the H group reached significance [OR: 2.26 (1.45 to 3.53)].