Figure 6. Epitope mapping by ZIKV DI/DII- and DIII-expressing yeast clones.

Each mAb (10 μg/ml) were incubated with domain-specific yeast clones and analyzed by FACS. Positive control mAbs 4G2, ZV48, and ZV-67 were used for specific recognition of DI/II and DIII. Negative control mAb MERS-4 was previously isolated against MERS-CoV. C-Myc is a protein tag used for monitoring DI/II and DIII expression under induction condition.