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. 2017 Mar 6;8(21):34245–34257. doi: 10.18632/oncotarget.15939

Figure 3. Genomic features of late-onset SD-NRT.

Figure 3

Numbers of (A) Copy number variations (CNV) and (B) single nucleotide variants observed in tumors belonging to (C) the “RT” group (left panel) and to the “SD-NRT” group (right panel). Grey bars indicate tumors (A, B) for which both tumor and germline DNA could be analysed and numbers of SNV (b) are indicated by the scales that range from 0 to 40. White bars indicate tumors for which no germline DNA could be analysed and numbers of SNV (B) are indicated by the scales that range from 0 to 400. ND: not done. (C) CNV profile on tumor 182, harboring chromothripsis features on multiple chromosomes, including chromosome 22 that shows a homozygous deletion at SMARCB1 locus.