Table 4. Correlation between pMKK4 score and clinicopathological characteristics of 96 CRC cases in the pilot-set.
| pMKK4 score | P | ||||
|---|---|---|---|---|---|
| Low score | High score | ||||
| negative (–) | weak (+) | moderate (++) | strong (+++) | ||
| Gender | 0.797 | ||||
| Male | 13 | 22 | 17 | 3 | |
| Female | 11 | 15 | 14 | 1 | |
| Age (years) | 0.185 | ||||
| < 60 | 12 | 18 | 11 | 1 | |
| ≥ 60 | 12 | 19 | 20 | 3 | |
| Tumor Differentiation | 0.976 | ||||
| Poor | 2 | 5 | 4 | 0 | |
| Moderate | 17 | 22 | 21 | 3 | |
| Well | 5 | 10 | 6 | 1 | |
| KRAS mutation | 0.237 | ||||
| Wild type | 17 | 24 | 26 | 3 | |
| Mutated | 7 | 13 | 5 | 1 | |
| Invasive Depth | 0.106 | ||||
| T1 | 1 | 1 | 5 | 0 | |
| T2 | 4 | 4 | 7 | 2 | |
| T3 | 13 | 26 | 16 | 2 | |
| T4 | 6 | 6 | 3 | 0 | |
| LN metastasis | 0.584 | ||||
| Absent | 13 | 10 | 16 | 3 | |
| Present | 11 | 27 | 15 | 1 | |
| Distant metastasis | 0.017 | ||||
| Absent | 16 | 34 | 28 | 4 | |
| Present | 8 | 3 | 3 | 0 | |
| Liver metastasis | 0.008 | ||||
| Absent | 18 | 36 | 28 | 4 | |
| Present | 6 | 1 | 1 | 0 | |
| TNM Stage | 0.089 | ||||
| I | 5 | 2 | 7 | 2 | |
| II | 6 | 9 | 7 | 1 | |
| III | 5 | 23 | 14 | 1 | |
| IV | 8 | 3 | 3 | 0 | |