Table 6. Univariate Cox analysis of potential prognostic factors influencing DFS and OS.

	DFS			OS
	Hazard Ratio	95% CI	P	Hazard Ratio	95% CI	P
Gender	1.264	0.861, 1.727	0.264	1.173	0.805, 1.711	0.406
Age (< 60 VS. ≥ 60)	1.067	0.752, 1.515	0.715	1.130	0.772, 1.655	0.503
Tumor Differentiation	1.706	1.175, 2.477	0.005	1.768	1.184, 2.641	0.005
pMKK4 Score	0.379	0.249, 0.577	< 0.001	0.498	0.328, 0.756	0.001
TNM Stage	3.807	2.912, 4.976	< 0.001	4.871	3.660, 6.483	< 0.001