Figure 2. High Notch3 levels are associated with poor prognosis.
(A) Notch3 levels were assessed in 59 paraffin-embedded formalin-fixed urothelial cancer tissues and matched non-tumor tissues (from the same patient) by immunohistochemistry. Bars show the number of patients with no (IRS = 0), low (IRS = 1–4), moderate (IRS = 5–8), and high (IRS = 9–12) expression in urothelial cancer tissues. (B) Kaplan-Meier curve for overall survival was compared according to Notch3 levels in human urothelial cancer tissues. Samples were divided as low (IRS < 4) and high (IRS ≥ 4).