Figure 5. Notch3 knockdown renders urothelial cancer cells sensitive to a 15-day treatment with cisplatin.

(A) Cell viability of T24 cells under different treatment was detected by CCK-8 assay. (B) To assess the formation of cisplatin-resistant colonies, T24 cells were either untreated (control) or treated with Notch3-shRNA alone, cisplatin alone, or cisplatin plus Notch3-shRNA, and cultured for 15 days.