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. 2017 Mar 29;8(21):34687–34697. doi: 10.18632/oncotarget.16670

Figure 1. Somatic non-synonymous mutations in conserved residues of JAK1.

Figure 1

(A) Representative electropherograms of identified JAK1 mutations from 3 patients with ALL. Heterozygous mutations are indicated by double peaks. (B) Schematic diagram of JAK1 protein structure and location of affected residues. Somatic mutations are indicated by arrows. (C) Alignment of amino acid sequences of JAK1 residues.