Table 3. Characteristics of ALL patients with JAK1 mutations.
P | G | Age | Lineage | WBC (× 109/L) | Fusion Gene | Complex karyotype | AA substitution | Relapse |
---|---|---|---|---|---|---|---|---|
1 | M | 15 | B-ALL | 18.55 | - | - | Ser646Pro | + |
2 | M | 32 | T-ALL | 25.2 | - | - | Ala639Gly | - |
3 | M | 42 | T-ALL | 320.29 | - | - | Pro960Ser | + |
4 | M | 17 | B-ALL | 11 | - | + | Tyr652His | + |
5 | M | 3 | B-ALL | 45.95 | TCF3-PBX1 | + | Asn973Lys | + |
Abbreviations: ALL, acute lymphoblastic leukemia; P, patient; G, gender; WBC, white blood cell; AA, amino acid; M, male.