Figure 6. Effect of CysLT1R on proinflammatory mediators detected in AOM/DSS colon and serum.
Cytokines were quantified from the AOM/DSS serum (n = 3–7) and colon samples (n = 2–7) using a multiplex sandwich immunoassay format. (A) Inflammatory mediators (IL-1β, TNFα, CXCL1, IFN-γ, IL-6, IL-10 and IL-2) quantified from colon lysates. (B) Inflammatory mediators (IL-1β, TNFα, CXCL1, IFN-γ, IL-6, IL-10 and IL-5) quantified from serum. Quantitative data are shown as the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 by t-test or Mann-Whitney test. Values below the detection level were labeled as (†).