Table 3. Univariate analysis based identification of prognostic factors for PFS and OS in ENKTL patients.
| Variables | Progression-free survival | Overall survival | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (≤ 45 or > 45) | 1.149 | 0.675–1.958 | 0.609 | 1.535 | 0.805–2.926 | 0.193 |
| Gender (Male or Female) | 0.682 | 0.360–1.293 | 0.241 | 0.700 | 0.319–1.533 | 0.372 |
| Ann Arbor Stage (IE or IIE) | 1.940 | 1.102–3.416 | 0.022 | 2.482 | 1.268–4.859 | 0.008 |
| LDH Elevated | 1.203 | 0.673–2.151 | 0.532 | 1.410 | 0.707–2.813 | 0.329 |
| ECOG (0–1 or > 1) | 2.487 | 0.898–6.893 | 0.080 | 4.037 | 1.423–11.450 | 0.009 |
| IPI (0–1 or > 1) | 1.357 | 0.540–3.410 | 0.516 | 2.784 | 1.152–6.729 | 0.023 |
| KPI (0–1 or > 1) | 1.233 | 0.697–2.182 | 0.472 | 1.716 | 0.882–3.328 | 0.112 |
| B symptoms (Yes or No) | 1.354 | 0.802–2.303 | 0.254 | 1.336 | 0.696–2.565 | 0.383 |
| βLRI (≤ 4.87 or > 4.87) | 2.093 | 1.138–3.850 | 0.018 | 2.798 | 1.405–5.572 | 0.003 |
| LLRI (≤ 128.44 or > 128.44) | 1.549 | 0.911–2.626 | 0.104 | 1.977 | 1.030–3.794 | 0.040 |
| NLR (≤ 2.36 or > 2.36) | 1.045 | 0.618–1.767 | 0.870 | 1.479 | 0.771–2.838 | 0.239 |
| dNLR (≤ 1.42 or > 1.42) | 1.373 | 0.760–2.481 | 0.294 | 2.714 | 1.132–6.500 | 0.025 |
| M/GLR (≤ 2.65 or > 2.65) | 1.371 | 0.807–2.330 | 0.244 | 2.141 | 1.074–4.266 | 0.030 |
| PLR (≤ 220.13 or > 220.13) | 1.546 | 0.798–2.994 | 0.197 | 1.786 | 0.815–3.918 | 0.148 |