Table 4. Incidence density rates and hazard ratios for different subtypes of pathologic fracture in the HSCT group comparing with the non-HSCT group.
| Subtypes of fracture (ICD-9-CM code) | Non-HSCT group | HSCT group | HR (95% CI) | |||
|---|---|---|---|---|---|---|
| Event no. | IR | Event no. | IR | Crude | Adjusteda(95% CI) | |
| Pathologic fracture (733.1) | 4 | 0.18 | 0 | 0.00 | - | - |
| Pathologic fracture, unspecified site (733.10) | 4 | 0.18 | 1 | 0.26 | 1.43 (0.16–12.8) | 1.72 (0.18–16.8) |
| Pathologic fracture of humerus (733.11) | 4 | 0.18 | 2 | 0.51 | 2.83 (0.52–15.5) | 3.42 (0.60–19.7) |
| Pathologic fracture of distal radius and ulna (733.12) | 0 | 0.00 | 0 | 0.00 | - | - |
| Pathologic fracture of vertebrae (733.13) | 30 | 1.34 | 13 | 3.34 | 2.43 (1.27–4.67)** | 2.73 (1.40–5.33)** |
| Pathologic fracture of neck of femur (733.14) | 4 | 0.18 | 1 | 0.26 | 1.35 (0.15–12.2) | 1.86 (0.20–17.6) |
| Pathologic fracture of other specified part of femur (733.15) | 2 | 0.09 | 0 | 0.00 | - | - |
| Pathologic fracture of tibia or fibula (733.16) | 2 | 0.09 | 2 | 0.51 | 5.67 (0.79–40.5) | 9.30 (0.97–89.4) |
| Pathologic fracture of other specified site (733.19) | 4 | 0.18 | 0 | 0.00 | - | - |
HSCT: hematopoietic stem cell transplant; IR: incidence density rate per 1000 person-years; HR: hazard ratio; CI: confidence interval.
aModel adjusting for sex, age, diabetes mellitus, hyperlipidemia, hypertension, coronary artery disease, depression, stroke, chronic obstructive pulmonary disease, chronic kidney disease, and the type of cancer.
**P < 0.01.