Table 1. correlation between miR-509-3-5P expression and clinicopathological parameters in GC (n = 54).
Parameters | category | No. | MiR-509-3-5P expression | p | |
---|---|---|---|---|---|
low | high | ||||
Age | 0.055128 | ||||
< 65 | 26 | 17 | 9 | ||
≥ 65 | 28 | 11 | 17 | ||
Gender | 0.439419 | ||||
Male | 38 | 21 | 17 | ||
Female | 16 | 7 | 9 | ||
T stage1 | 0.022088* | ||||
T2 | 5 | 0 | 5 | ||
T3 | 21 | 10 | 11 | ||
T4 | 28 | 18 | 10 | ||
N stage | N0 | 11 | 3 | 8 | 0.027214* |
N1 | 12 | 4 | 8 | ||
N2 | 13 | 7 | 6 | ||
N3 | 18 | 14 | 4 | ||
UICC stage2 | II | 17 | 4 | 13 | 0.007740** |
III | 37 | 24 | 13 | ||
Nerve invasion | Yes | 29 | 17 | 12 | 0.283639 |
No | 25 | 11 | 14 | ||
Vessel invasion | Yes | 29 | 14 | 15 | 0.571098 |
No | 25 | 14 | 11 | ||
Differentiation3 | High | 3 | 0 | 3 | 0.000101*** |
Moderate | 19 | 4 | 15 | ||
Low | 32 | 24 | 8 | ||
Tumor size | ≤ 3 | 23 | 12 | 11 | 0.967456 |
> 3 | 31 | 16 | 15 |
1,2There is no T1 stage tumor or M1 patients in our GC tissues microarray.
3Low differentiation includes poor differentiation, mucinous adenocarcinoma, and signet ring cell carcinoma.
*p < 0.05, **p < 0.01,***p < 0.001.