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. 2017 Mar 23;8(21):34980–34991. doi: 10.18632/oncotarget.16507

Table 1. Development of SCNT embryos derived from donor cells with Dnmt1s knockdown.

Group No. embryoscultured (Rep.) No. embryos cleaved(% ± SEM) No. blastocysts(% ± SEM) Blastocystcell numbers(mean ± SEM) *
control 163 (5) 138 (84.75 ± 1.98) 33 (20.37 ± 1.15)a 35 ± 2 (n=32)
siRNA- negative 167 (5) 139 (83.23 ± 1.43) 36 (21.50 ± 1.06)a 34 ± 3 (n=34)
siRNA- positive 176 (5) 153 (87.28 ± 1.73) 55 (31.33 ± 1.49)b 38 ± 3 (n=29)

*Blastocyst cell numbers, less than 16, were not included, and 25 blastocysts in the siRNA-positive group were used for molecular analysis.

a-bValues in the same column with different superscripts differ significantly (P < 0.05).