Figure 8. PAH delivered HVJ-E to tumor sites in vivo.

The C57BL/6 and SCID mice that had been inoculated subcutaneously with (A) B16F10 (10⁶) and (B) PC3 (10⁶) at day 0 were treated i.p. with Salmonella (10⁶ CFU/100 μL) at day 8. Mice bearing tumors ranging from 50–100 mm³ were injected i.p. with PHS (10⁶ cfu), and the numbers of Salmonella in the tumors, livers, and spleens were determined at various time points. The data are reported as the means ± SD (n = 4–5); (C) B16F10 and PC3 tumor tissues were lysed and the functional protein of HVJ-E was performed on day 1. This experiment was repeated with similar results. The cropped blots are displayed.