Table 1. Molecular docking results of ginkgolic acids on SUMO activating enzyme E1.
Ligand | Lowest binding Energy(kcal/mol)) | No. of interacting amino acids | Amino acids showing H-bonds | |
---|---|---|---|---|
1. | C17:1 Δ10 | 12.27 ± 0.19 | 9 | ARG 21 |
2. | C15:1Δ8 | 11.04 ± 0.54 | 12 | ILE 384 |
3. | C15:1 Δ10 | 11.44 ± 0.43 | 13 | GLY 26 |
4. | C15:0 | 11.12 ± 0.37 | 13 | ALA 386 |
5. | C13:0 | 10.28 ± 0.24 | 11 | THR 141 |
6. | C17:1Δ8 | 11.46 ± 0.34 | 9 | - |
7. | C17:0 | 11.48 ± 0.79 | 8 | ILE 96 |