Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 4;8(21):35138–35153. doi: 10.18632/oncotarget.16812

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © 2017 Maitra et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

The ELISA for IFN-α,-β and -γ are shown in order in three graphs (a), (b) & (c). TLR-3 down regulated cells showed no increase in release of the soluble cytokines upon reovirus infection at a dose of 5 MOI. On the contrary, HCT116 control cells did show a rise in release of the three classes of interferons upon reovirus infection at 5 MOI. In case of IFN-α there was a significant increase (p≤ 0.05) of cytokine productions at all 4 time points namely 6, 12, 24 and 48 hours as represented by *. In case of IFN-β the significance (p≤ 0.05) was observed in control cells treated and untreated at 6 and 12 hours where as the IFN-γ showed a significant difference in the same group at 24 and 48 hours.