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. 2017 Apr 4;8(21):35138–35153. doi: 10.18632/oncotarget.16812

Figure 8.

Figure 8

(a) Morphometric analysis of IHC stained HCT116 cells and HCT116-TLR3 KO cells 24 hours post reovirus treatment with antibody raised against reovirus sigma 1 capsid protein. There is a 1.85 -fold increase in expression of the sigma1 protein in TLR3 KO cells (p=0.0244). (b) Graphical representation of the expression of RNA dependent RNA polymerase lambda 3 in HCT116 cells and HCT116-TLR3 KO cells 24 hours post reovirus treatment as measured by real time PCR. A 1.91-fold increase in expression was observed in the TLR3 KO cells. (p=0.045).