Table 1. Patient and TSCC/BOTSCC characteristics.

Patient and tumor characteristics		HPV+TSCC/BOTSCC (N= 279)		HPV-TSCC/BOTSCC (N= 46)		All TSCC/BOTSCC (N= 325)
		N	%	N	%	N	%
Age	Mean (years)	60.0		63.0		60
	Median (years)	59		62		60.0
	Range (years)	30-84		46-85		30-84
Diagnose	malignant neoplasm of the base of tongue (C01.9)	73	26%	14	30%	87	27%
	malignant neoplasm of the tonsil (C09.0-9)	206	74%	37	80%	243	75%
Sex	female	65	23%	9	20%	74	23%
	male	214	77%	37	80%	251	77%
Tumour differentiation	poorly	180	65%	29	63%	209	64%
	moderatley	75	27%	12	26%	87	27%
	well	16	6%	5	11%	21	6%
	undefined	8	3%	0	0%	8	2%
Tumour size	T1	78	28%	6	13%	84	26%
	T2	107	38%	12	26%	119	37%
	T3	52	19%	14	30%	66	20%
	T4	42	15%	14	30%	56	17%
Nodal disease	N0	37	13%	17	37%	54	17%
	N1	61	22%	3	7%	64	20%
	N2a	37	13%	4	9%	41	13%
	N2b	109	39%	12	26%	121	37%
	N2c	25	9%	7	15%	32	10%
	N3	8	3%	3	7%	11	3%
	NX	2	1%	0	0%	2	1%
Distant metastasis	M0	275	99%	46	100%	321	99%
	M1	2	1%	0	0%	2	1%
	MX	2	1%	0	0%	2	1%
Tumour Stage	I	4	1%	5	11%	9	3%
	II	18	6%	3	7%	21	6%
	III	65	23%	9	20%	74	23%
	IVa	178	64%	25	54%	203	62%
	IVb	9	3%	4	9%	13	4%
	IVc	2	1%	0	0%	2	1%
	Unknown	3	1%	0	0%	3	1%
Treatment	Induction chemotherapy and radiation	22	8%	7	15%	29	9%
		93	33%	5	11%	98	30%
	Radiation	115	41%	24	52%	139	43%
		47	17%	7	15%	54	17%
	Palliative	2	1%	3	7%	5	2%
Brachytherapy boost	Not administered	207	74%	33	72%	240	74%
	Administered	70	25%	10	22%	80	25%
Concomittant Cetuximab	Not administered	225	81%	40	87%	265	82%
	Administered	52	19%	3	7%	55	17%
Smoking	Never	105	38%	4	9%	109	34%
	Former (>15 years ago)	54	19%	1	2%	55	17%
	Former (<15 years ago)	53	19%	4	9%	57	18%
	Current upon diagnosis	67	24%	35	76%	103	32%
	Unknown	0	0%	2	4%	2	1%