Table 2. Key Findings in IBD subsets .
|
Contributing triggers and disease
features |
Types of disease | |
| Conventional IBD | Monogenic IBD | |
| Environmental factors | stronger | weaker |
| Genetic background | Complex | Mendelian |
| Frequency of subtypes | UC | CD |
| The course of disease | Milder | Severe |
| Response to therapy | Good | Poor |
| Atypical finding in endoscopy and histology | Lesser | More |
| Age of onset | >7 Yrs | <6Yrs |
| Perianal disease | Lesser | More |
| Consanguinity | Important | Essential |
| Sexuality | A subtle difference | A male predominance |