Table 1.

Demographic information and clinical characteristics (n = 18)

Age, yr mean (SD) [range yr]	36.4 (12.5) [20–56]
Male, n (%)	11 (61.1)
Caucasian, n (%)	10 (55.6)
Special diet, n (%)	8 (44.4)
Smoker, n (%)	12 (67.7)
Diabetes mellitus type 2, n (%)	2 (11.1)
Hyperlipidemia, n (%)	6 (33.3)
Hypertension, n (%)	2 (11.1)
Polydipsia, n (%)	2 (11.1)
Maximum stabilized CLZ dose, mg/day mean (SD) [range mg/day]	441.7 (171.8) [100–800]
CLZ level, mcg/L mean (SD) [range mcg/L]	386.9 (177.7) [91–835]
Norclozapine level, mcg/L mean (SD) [range mcg/L]	210.9 (97.7) [31–595]
Total CLZ level, mcg/L mean (SD) [range mcg/L]	603.9 (263.0) [122–1430]

Special diet includes the following: low salt, low cholesterol, high protein, gluten free or high calorie