Table 1.

Baseline and follow-up fecal microbe composition^a of 22 men with prostate cancer over the duration of a presurgical weight loss trial.

	Weight loss group (n=11)					Control group (n=11)					Between Groups
	Baseline		Follow-up		Changeb	Baseline		Follow-up		Changeb	Changec
	Median	IQR	Median	IQR	p-value	Median	IQR	Median	IQR	p-value	p-value
Actinobacteria	0.0236	0.0115, 0.0880	0.0348	0.0072, 0.0466	0.859	0.0179	0.0115, 0.0313	0.0296	0.0194, 0.0457	0.062	0.270
Corynebacterium	0.0037	0.0003, 0.0116	0.0011	0.0001, 0.0078	0.929	0.0030	0.0007, 0.0227	0.0054	0.0008, 0.0684	0.182	0.898
Bifidobacterium	0.0026	0.0005, 0.0052	0.0018	0.0001, 0.0161	0.374	0.0031	0.0007, 0.0102	0.0092	0.0072, 0.0182	0.110	0.401
Bacteroidetes	0.1845	0.1180, 0.4433	0.2578	0.1770, 0.3510	0.859	0.1911	0.0754, 0.3706	0.1572	0.1272, 0.2604	0.534	0.699
Bacteroides	0.2078	0.0623, 0.3674	0.1603	0.1112, 0.2630	0.213	0.1150	0.0159, 0.1723	0.0636	0.0497, 0.2789	0.374	0.847
Prevotella	0.0059	0.0003, 0.0305	0.0038	0.0002, 0.0325	0.424	0.0142	0.0041, 0.0269	0.0188	0.0025, 0.0439	0.859	0.652
Firmicutes	0.6508	0.5294, 0.7729	0.5899	0.4636, 0.7398	0.424	0.5702	0.3658, 0.7935	0.7164	0.5925, 0.7861	0.110	0.151
Blautia	0.1124	0.0563, 0.2068	0.1678	0.0257, 0.2425	0.534	0.0505	0.0294, 0.0887	0.0586	0.0293, 0.1989	0.477	0.519
Faecalibacterium	0.0703	0.0507, 0.0921	0.0566	0.0381, 0.1296	1.000	0.0669	0.0246, 0.0972	0.0290	0.0079, 0.0660	0.286	0.332
Roseburia	0.0500	0.0178, 0.0879	0.0485	0.0012, 0.0566	0.155	0.0280	0.0123, 0.0575	0.0108	0.0031, 0.0604	0.790	0.847
Ruminococcus	0.0207	0.0056, 0.0439	0.0190	0.0108, 0.0392	0.790	0.0192	0.0111, 0.0535	0.0120	0.0065, 0.0298	0.328	0.478
Clostridium	0.0058	0.0013, 0.0098	0.0056	0.0034, 0.0077	0.929	0.0073	0.0010, 0.0108	0.0054	0.0005, 0.0126	1.000	0.217
SMB53	0.0053	0.0009, 0.0113	0.0060	0.0002, 0.0204	0.424	0.0052	0.0004, 0.0185	0.0044	0.0023, 0.0096	0.929	0.847
Finegoldia	0.0031	0.0006, 0.0088	0.0015	0.0007, 0.0074	0.534	0.0032	0.0005, 0.0105	0.0100	0.0019, 0.0514	0.075	0.974
Streptococcus	0.0030	0.0016, 0.0309	0.0052	0.0022, 0.0589	0.722	0.0061	0.0015, 0.0254	0.0054	0.0027, 0.0178	0.790	0.519
Allobaculum	0.0007	0.0002, 0.0019	0.0013	0.0003, 0.0474	0.374	0.0006	0.0001, 0.0148	0.0008	0.0002, 0.0080	1.000	0.797
Lactobacillus	0.0004	0.0003, 0.0037	0.0009	0.0003, 0.0044	0.859	0.0021	0.0006, 0.0113	0.0028	0.0007, 0.0041	0.424	0.974
Proteobacteria	0.0223	0.0087, 0.0816	0.0328	0.0201, 0.1392	0.657	0.1434	0.0239, 0.1910	0.0513	0.0172, 0.0899	0.131	0.133
Escherichia	0.0004	0.0002, 0.0049	0.0013	0.0003, 0.0050	0.859	0.0043	0.0008, 0.0273	0.0029	0.0004, 0.0078	0.477	0.300
F:B Ratiod	1.81	1.20, 5.25	2.81	1.62, 5.29	0.790	4.44	1.88, 17.19	3.78	1.63, 5.67	0.155	0.365

^aFour major phyla with species representing >0.01% of average composition of all study samples.

^bWilcoxon Signed Rank Test was used to determine differences over time within groups.

^cMann-Whitney U Test was used to determine difference between groups over time.

^dFirmicutes : Bacteroidetes Ratio.