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. 2017 Jun 14;7:3451. doi: 10.1038/s41598-017-03759-w

Figure 5.

Figure 5

Depletion of IL-6 from chondrocyte conditioned media ablates IL-6 secretion from synovial fibroblasts. Synovial fibroblasts were cultured in chondrocyte conditioned media which had been treated with anti-IL-6 antibody or anti-IgG antibody during immunoprecipitation. Depletion of IL-6 in the chondrocyte conditioned media ablated the ability of fibroblasts to secrete elevated IL-6 titres in response to chondrocyte conditioned media. Data are mean ± SEM. Statistical significance was determined by one-way ANOVA ***p < 0.001.