Table 1.
Variables | Glaucoma patients with DH | Glaucoma patients with focal LC defect without DH | P Value |
---|---|---|---|
Patients (no.) | 98 | 37 | |
Age at diagnosis (yrs) | 60.88 ± 12.09 | 60.05 ± 12.32 | 0.921* |
Male, no. (%) | 36 (36.7%) | 8 (21.6%) | 0.104† |
Systemic factors, no (%) | |||
Diabetes mellitus | 18 (18.4%) | 5 (13.5%) | 0.613† |
Hypertension | 25 (25.5%) | 6 (16.2%) | 0.181† |
Medication of aspirin | 24 (24.5%) | 8 (21.6%) | 0.823† |
SE refraction error (D) | −1.18 ± 2.99 | −1.63 ± 2.63 | 0.540* |
Axial length (mm) | 24.16 ± 1.66 | 24.26 ± 1.49 | 0.775* |
Central corneal thickness (μm) | 526.43 ± 35.01 | 524.86 ± 31.84 | 0.115* |
Baseline IOP (mmHg) | 15.24 ± 3.33 | 16.35 ± 3.00 | 0.604* |
Mean follow-up IOP (mmHg) | 14.30 ± 2.63 | 14.02 ± 3.70 | 0.138* |
Peak follow-up IOP (mmHg) | 15.70 ± 3.21 | 15.62 ± 3.34 | 0.974* |
IOP fluctuation (mmHg) | 4.27 ± 1.61 | 4.62 ± 1.01 | 0.932* |
Ocular characteristics | |||
Disc area (mm2) | 2.17 ± 0.45 | 2.16 ± 0.44 | 0.620* |
Average RNFL thickness (μm) | 79.91 ± 11.69 | 81.51 ± 10.60 | 0.467* |
Number of DH | 2.13 ± 1.09 | 0 | |
Recurrent DH, no (%) | 62 (63.3%) | 0 | |
Number of eyes with focal LC defect, no (%) | 36 (36.7%) | 37 (100%) | |
Focal LC defect at the DH site, no (%) | 20 (55.6%) | ||
Focal LC defect outside the DH site, no (%) | 16 (44.4%) | ||
Baseline VF examination | |||
MD (dB) | −3.98 ± 4.82 | −3.54 ± 3.10 | 0.612* |
PSD (dB) | 4.59 ± 3.77 | 4.65 ± 3.06 | 0.928* |
Follow-up duration (mos) | 59.48 ± 9.21 | 58.67 ± 9.65 | 0.470* |
Number of VF examination (no.) | 7.02 ± 2.24 | 6.47 ± 1.21 | 0.526* |
D, diopters; IOP, intraocular pressure; RNFL, retinal nerve fiber layer; DH, disc hemorrhage; LC, lamina cribrosa; MD, mean deviation; PSD, pattern standard deviation; VF, visual field.
Data are mean ± standard deviation unless otherwise indicated.
*Student t-test.
†Chi-square test.
Data are mean ± standard deviation unless otherwise indicated.