Table 2.
Variables | Progression (n = 45) | Stable (n = 53) | P Value |
---|---|---|---|
Age at diagnosis (yrs) | 61.62 ± 12.21 | 60.26 ± 12.07 | 0.582* |
Male, no. (%) | 22 (41.5%) | 14 (31.1%) | 0.197† |
Systemic factors, no (%) | |||
Diabetes mellitus | 8 (17.8%) | 10 (18.9%) | 0.551† |
Hypertension | 11 (24.4%) | 14 (26.4%) | 0.505† |
Medication of aspirin | 11 (24.4%) | 13 (24.5%) | 0.590† |
SE refraction error (D) | −1.51 ± 3.19 | −0.78 ± 2.75 | 0.389* |
Axial length (mm) | 24.20 ± 1.47 | 24.10 ± 1.87 | 0.846* |
Central corneal thickness (μm) | 519.05 ± 39.21 | 531.62 ± 31.45 | 0.234* |
Baseline IOP (mmHg) | 14.82 ± 3.57 | 15.55 ± 3.14 | 0.337* |
Mean follow-up IOP (mmHg) | 14.04 ± 2.92 | 14.52 ± 2.36 | 0.367* |
Peak follow-up IOP (mmHg) | 15.66 ± 3.35 | 15.75 ± 3.07 | 0.885* |
IOP fluctuation (mmHg) | 4.35 ± 1.63 | 4.17 ± 4.59 | 0.583* |
Optic disc characteristics | |||
Disc area (mm2) | 2.20 ± 0.51 | 2.14 ± 0.38 | 0.547* |
Average RNFL thickness (μm) | 79.82 ± 12.74 | 79.97 ± 10.84 | 0.950* |
Number of DH | 2.15 ± 1.10 | 2.11 ± 1.08 | 0.849* |
Recurrent DH, no (%) | 29 (64.4%) | 33 (62.3%) | 0.495* |
Number of eyes with focal LC defect, no (%) | 26 (57.8%) | 10 (18.9%) | <0.001 † |
Focal LC defect at the DH site, no (%) | 17 (37.8%) | 3 (5.7%) | 0.001 † |
Focal LC defect outside the DH site, no (%) | 9 (20.0%) | 7 (13.2%) | 0.263 |
Baseline VF examination | −4.22 ± 3.69 | −3.77 ± 4.91 | 0.654* |
MD (dB) | 4.31 ± 3.69 | 4.84 ± 3.86 | 0.499* |
PSD (dB) | 72.29 ± 12.24 | 72.64 ± 12.16 | 0.161* |
Follow-up duration (mos) |
D, diopters; IOP, intraocular pressure; RNFL, retinal nerve fiber layer; DH, disc hemorrhage; LC, lamina cribrosa; MD, mean deviation; PSD, pattern standard deviation; VF, visual field.
*Student t-test.
†Chi-square test.
Data are mean ± standard deviation unless otherwise indicated.
Factors with statistical significance are shown in bold.