Table 2.

Associations between plasma Wnt5a, sFRP3, the Wnt5a/sFRP3 ratio and ventricular function in patients with DCM.

Variable	All patients	Wnt5a	sFRP3	Wnt ratio
Pulmonary artery systolic pressure (mm Hg)	37 ± 12	0.35***	0.05	0.33**
Mean pulmonary artery pressure (mm Hg)	24 ± 10	0.26**	0.12	0.24*
Pulmonary capillary wedge pressure (mm Hg)	14 (8, 33)	0.25*	0.21*	0.17
Left atrial area (cm2)	28 ± 6	0.24*	0.31**	0.06
E/A ratio	1.31 (0.77, 2.07)	0.40***	0.34**	0.23*
Cardiac output (l/min)	4.9 ± 1.4	−0.05	−0.15	0.01
Left ventricular end-systolic volume (ml)	191 (141, 269)	0.16	0.13	0.04
Left ventricular end-diastolic volume (ml)	264 (214, 327)	0.15	0.14	0.07
Left ventricular ejection fraction (%)	27 ± 10	−0.17	−0.08	−0.14
Right ventricular end-systolic volume (ml)	110 (82, 161)	0.32**	0.23*	0.14
Right ventricular end-diastolic volume (ml)	188 (155, 241)	0.30**	0.25*	0.19
Right ventricular ejection fraction (%)	39 ± 13	−0.27*	−0.18	−0.22*

Data are given as mean ± standard deviation or median (25^th/75^th percentile) depending on distribution. *p < 0.05, **p < 0.01, ***p < 0.001.