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. 2017 Jun 14;7:3533. doi: 10.1038/s41598-017-03807-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Schematic of metabolic pathways in A. thaliana focusing on the regulation of AtPGDH1 and AtPGDH3. Amino acids are denoted by standard 3-letter codes; Glc, glucose; Pyr, pyruvate; OAA, oxaloacetate; RuBP, ribulose 1,5-bisphosphate; HSer, homoserine; HCys, homocysteine; AdoMet, S-adenosyl-l-methionine; X, methyl acceptor; Rubisco, ribulose 1,5-bisphosphate carboxylase/oxygenase. Dashed and dotted lines indicate glycolysis and photorespiration, respectively. Red arrows and blue lines indicate activation and inhibition of AtPGDH1 and AtPGDH3, respectively. Asterisks indicate sulfur-containing metabolites. Presented reactions do not include all known reactions.