Table 2.
SNPs association results in Polish discoid lupus erythematosus (DLE) and systemic lupus erythematosus (SLE) patients
| SNP (gene) | Allele/genotype | N (%) | Fisher’s p-value | Bonferroni corrected p-value (pB) | N (%) | Fisher’s p-value | Bonferroni corrected p-value (pB) | |
|---|---|---|---|---|---|---|---|---|
| Controls | SLE | DLE | ||||||
| rs7574865 (STAT4) | G | 79 (79.0) | 47 (67.1) | 0.1190 | 0.3570 | 28 (66.7) | 0.1379 | 0.4137 |
| T | 21 (21.0) | 23 (32.9) | 14 (33.3) | |||||
| GG | 29 (58.0) | 17 (48.6) | 0.5075 | 1.0000 | 10 (47.6) | 0.4459 | 1.0000 | |
| GT | 21 (42.0) | 13 (37.1) | 0.8222 | 1.0000 | 8 (38.1) | 0.7977 | 1.0000 | |
| TT | 0 (0.0) | 5 (14.3) | 0.0099 | 0.0297 | 3 (14.3) | 0.0233 | 0.0699 | |
| rs1150754 (TNXB) | A | 17 (17.0) | 24 (34.3) | 0.0112 | 0.0336 | 5 (11.9) | 0.4669 | 1.0000 |
| G | 83 (83.0) | 46 (65.7) | 37 (88.1) | |||||
| AA | 0 (0.0) | 0 (0.0) | 1.0000 | 1.0000 | 0 (0.0) | 1.0000 | 1.0000 | |
| GA | 17 (34.0) | 24 (68.6) | 0.0021 | 0.0063 | 5 (23.8) | 0.5748 | 1.0000 | |
| GG | 33 (66.0) | 11 (31.4) | 0.0021 | 0.0063 | 16 (76.2) | 0.5748 | 1.0000 | |
| rs1143679 (ITGAM) | A | 11 (11.0) | 17 (24.3) | 0.0343 | 0.1029 | 9 (21.4) | 0.1175 | 0.3525 |
| G | 89 (89.0) | 53 (75.7) | 33 (78.6) | |||||
| AA | 0 (0.0) | 1 (2.8) | 0.4118 | 1.0000 | 0 (0.0) | 1.0000 | 1.0000 | |
| GA | 11 (22.0) | 15 (42.9) | 0.0558 | 0.1674 | 9 (42.9) | 0.0894 | 0.2682 | |
| GG | 39 (78.0) | 19 (54.3) | 0.0324 | 0.0972 | 12 (57.1) | 0.0894 | 0.2682 | |