Table 3.

Sensitivity analysis for the SHAM and AB models

		PCa		DCa		RT50		T peak
Parameter	Description	SHAM	AB	SHAM	AB	SHAM	AB	SHAM	AB
g SERCA	Maximum pump rate of SERCA	−0.301	0.138	−1.217	−1.588	−1.515	−1.493	0	0
K SERCA	Half saturation of SERCA	0.351	−0.029	1.246	1.173	0	0	0	0
g CaB	Conductance of background Ca2+	0.050	0.024	0.0014	0.0357	0	0	0	0
g t	Conductance of transient outward K+	−3.355	0.280	−3.563	0.1959	−4.545	0	−3.846	0
g K1	Conductance inward rectifying K+	−0.304	0.080	−0.352	−0.0211	0	0	0	0
g Na	Conductance of inward Na+	−0.157	−0.027	8.7 × 10–5	−0.098	0	0	0	0
g ss	Conductance of steady state K+	−0.664	0.004	−0.744	−0.003	−1.515	0	0	0
V L	Potential when half LCC channels are open	−0.664	−0.087	3.242	−0.217	4.546	0	3.846	0
K L	Concentration at LCC inactivation	3.111	0.481	1.061	1.299	1.515	1.492	0	0
J L	Permeability of a single LCC	5.706	0.342	5.777	−0.132	7.576	−1.492	7.692	0
g NCX	Pump rate of NCX	−0.151	−0.335	−0.169	−0.302	0	0	0	0

Sensitivity values S_i,j, where i are the phenotypes and j are the tested parameters. In the case of the sensitivity being positive, an increase in the parameter will lead to an increase in the output. In the case of the sensitivity being negative, an increase in the parameter will lead to a decrease in the output.