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. 2015 Oct 22;5:36–41. doi: 10.1016/j.ymgmr.2015.09.006

Table 1b.

Comparison (Kruskal–Wallis) of dietary regimes regarding median Phe-concentrations (in μmol/l and in % above therapeutic limit), age, Phe-intake, adherence to amino acid mixture and burden of dietary regime for adolescents.

Dietary regime
1
2
3
4
5
p 2 df
n 5 10 13 10 3
Age [years]: median (range) 13 (10–15) 13 (10–15) 12 (10–13) 12 (10–15) 12 (11–15) 0.657 2.433 4
Age [years]: mean (SD) 12.2 (2.2) 12.5 (2.0) 11.5 (1.3) 12.5 (1.8) 12.7 (2.1)
Therapeutic range [μmol/l] 42–900 42–900 42–900 42–900 42–900
Median Phe-concentration [μmol/l] 361 565 532 627 629 0.831 1.577 4
Median Phe-concentration [μmol/l]: range 119–810 170–1157 119–844 184–812 584–802
Median Phe-concentration [μmol/l]: interquartile range(IQR) 232–713 310–716 298–655 360–757 584–802
Median Phe-concentrations > therapeutic range [%] 0 20 0 0 17 0.393 4.178 4
Median Phe-concentrations > therapeutic range [%]: range 0–50 0–83 0–33 0–17 0–33
Median Phe-concentrations > therapeutic range [%]: IQR 0–25 0–38 0–17 0–4 0–33
Phe intake [mg]: median (range) 500 (190–750) 355 (200–750) 350 (200–650) 420 (290–750) 550 (500–650) 0.212 5.835 4
Adherence to amino acid mixture: median (range) 5 (4–5) 5 (4–5) 5 (1–5) 5 (4–5) 5 (5–5) 0.405 4.018 4
Burden of dietary regime: median (range) 3 (2–5) 3 (1–4) 3 (1–5) 3 (1–5) 4 (2–3) 0.819 1.627 4