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. 2017 Mar 2;595(12):4089–4108. doi: 10.1113/JP273714

Figure 6. Fructose‐rich diet induces a CaMKII‐dependent ultrastructure remodelling.

Figure 6

A, transmission electron micrographs of left ventricle from WT and AC3I mice expressing the CaMKII inhibitor peptide AC3 at the whole heart level. FRD induced a clear remodelling of the WT mouse mitochondria, which is prevented in the AC3I mice. B, average data of the mitochondria area and mean Feret diameter. The mitochondria from the WT FRD mice are smaller than the WT CD mitochondria. Inhibition of CaMKII prevents this remodelling. * P < 0.05 vs all other groups, n = 3 mice per group.