Table 2.
Average LANG and LWH function during sinus rhythm before (Control) and after the administration of either GLIB (10 μm) or TOLB (1 μm)
| LANG | LWH | |||||
|---|---|---|---|---|---|---|
| Control | GLIB | TOLB | Control | GLIB | TOLB | |
| APD | 234 ± 17 | 237 ± 15 | 263 ± 5 | 179 ± 16 | 185 ± 26 | 200 ± 20* |
| MVO2 (μmol O2 g·min–1) | 1.4 ± 0.3 | 1.2 ± 0.3 | 2.1 ± 0.1 | 2.1 ± 0.2 | 1.2 ± 0.3*, † | 2.5 ± 0.7 |
| CFR (mL min−1) | 26 ± 4.0 | 11 ± 2.4*, † | 30 ± 8.0 | 26 ± 3.0 | 21 ± 6.2 | 37 ± 4.1 |
| LVDP (mmHg) | – | – | – | 81 ± 2.3 | 72 ± 12 | 93 ± 6.4* |
*Significantly different from the corresponding control.
†Significantly different from the corresponding TOLB measurement.
Values are the mean ± SE. LANG control: n = 7; LANG + GLIB: n = 4; LANG + TOLB: n = 4. LWH control: n = 6; LWH + GLIB: n = 3; LWH + TOLB: n = 5. Average MVO2, CFR and LVDP for Control and TOLB are the same data as shown in Table 1. Significance was tested using an ANOVA with Tukey post hoc comparisons.