Table 4.
Vitamin‐B status
| SNP+ (n = 4) | SNP− (n = 4) | Astronaut data (n = 49) | Normal range | |
|---|---|---|---|---|
| Vitamin B12, pmol/L | 416 (165–666) | 300 (131–468) | 557 (497–617) | 150–700 |
| Serum Folate, nmol/L | 30 (6–54) | 36 (24–48) | 33 (27–39) | 21–64 |
| Red Blood Cell Folate, ng/mL | 485 (195–776) | 720 (6–1433) | 447 (415–479) | 365–1043 |
| Methylmalonic Acid, nmol/L | 199 (77–321) | 137 (107–167) | 201 (177–225) | 73–271 |
| 2‐Methylcitric Acid, nmol/L | 141 (64–218) | 142 (90–194) | 157 (146–168) | 60–228 |
| Total Homocysteine, μmol/L | 9 (7.8–10.4) | 8 (5.7–9.6) | 8 (7.6–8.4) | 5.1–13.9 |
| Cystathionine, nmol/L | 159 (19–298) | 140 (78–201) | 175 (153–197) | 44–342 |
| Pyridoxal 5′‐phosphate, nmol/L | 85 (49–121) | 63 (27–98) | 108 (83–133) | 11–302 |
| 4‐pyridoxic acid, nmol/L | 16 (4–28) | 22 (0–50) | 45 (28–62) | 9–385 |
B‐vitamin status by one‐carbon genetics (SNP+, SNP−), in test subjects and astronauts. Astronaut data represent status at the time of blood collection for the 1C Study (Zwart et al. 2016) genetic analysis, and were not collected with any specific reference to flight.