Table 3.
Differentially expressed microRNA (mir)
| microRNA | micro RNA | ENSEMBL ID | Target mRNA | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Precursor | FC (TU vs. NO) | P value | adj P value | Symbol | FC (TU/NO) | P value | adj P value | ||
| hsa‐miR‐200b‐3p | hsa‐mir‐200b | −2.53 | 2.99E‐04 | 8.95E‐04 | |||||
| hsa‐miR‐200b‐5p | hsa‐mir‐200b | −2.34 | 1.48E‐04 | 5.10E‐04 | ENSG00000039068 | CDH1 | −2.38 | 3.53E‐07 | 1.40E‐06 |
| hsa‐miR‐200c‐3p | hsa‐mir‐200c | −39.12 | 6.84E‐09 | 3.59E‐07 | ENSG00000169554 | ZEB2 | 1.54 | 4.38E‐07 | 1.71E‐06 |
| hsa‐miR‐141‐5p | hsa‐mir‐141 | −30.31 | 1.25E‐07 | 2.29E‐06 | ENSG00000148516 | ZEB1 | |||
| hsa‐miR‐141‐3p | hsa‐mir‐141 | −17.64 | 1.08E‐07 | 2.18E‐06 | ENSG00000168036 | CTNNB1 | 1.16 | 3.20E‐03 | 5.71E‐03 |
| hsa‐miR‐429 | hsa‐mir‐429 | −2.34 | 4.36E‐05 | 1.83E‐04 | |||||
| hsa‐miR‐30a‐3p | hsa‐mir‐30a | −3.09 | 4.54E‐07 | 5.87E‐06 | |||||
| hsa‐miR‐30a‐5p | hsa‐mir‐30a | −2.32 | 1.50E‐05 | 7.48E‐05 | |||||
| hsa‐miR‐34a‐3p | hsa‐mir‐34a | 4.97 | 7.79E‐08 | 2.04E‐06 | ENSG00000167601 | AXL | 3.05 | 1.99E‐14 | 1,22E‐12 |
| hsa‐miR‐34a‐5p | hsa‐mir‐34a | 2.73 | 4.66E‐06 | 2.80E‐05 | ENSG00000157227 | MMP14 | 2.74 | 1.42E‐14 | 9.53E‐13 |
| hsa‐miR‐34c‐5p | hsa‐mir‐34c | 2.55 | 1.42E‐02 | 2.58E‐02 | |||||
| hsa‐miR‐203a‐3p | hsa‐mir‐203a | −2.26 | 1.44E‐02 | 2.60E‐02 | ENSG00000124216 | SNAIL1 | 1.78 | 1.21E‐03 | 2.33E‐03 |
| hsa‐miR‐10b‐5p | hsa‐mir‐10b | −2.72 | 1.44E‐09 | 1.26E‐07 | ENSG00000128710 | HOXD10 | −2.82 | 1.06E‐08 | 6.13E‐08 |
| ENSG00000156299 | TIAM1 | 1.92 | 5.66E‐09 | 3.55E‐08 | |||||
| hsa‐miR‐21‐3p | hsa‐mir‐21 | 6.23 | 1.05E‐07 | 2.18E‐06 | ENSG00000150593 | PDCD4 | 1.35 | 5.55E‐07 | 2.11E‐06 |
| ENSG00000140416 | TPM1 | 1.79 | 6.67E‐07 | 2.47E‐06 | |||||
| hsa‐miR‐31‐3p | hsa‐mir‐31 | −3.07 | 8.92E‐03 | 1.71E‐02 | ENSG00000156299 | TIAM1 | 1.92 | 5.66E‐09 | 3.55E‐08 |
| hsa‐miR‐155‐5p | hsa‐mir‐155 | 9.62 | 5.31E‐08 | 1.86E‐06 | ENSG00000067560 | RHOA | 1.16 | 3.05E‐04 | 6.59E‐04 |
| hsa‐miR‐194‐3p | hsa‐mir‐194‐2 | −3.21 | 3.47E‐04 | 1.00E‐03 | ENSG00000170558 | CDH2 | 1.79 | 2.69E‐05 | 7.13E‐05 |
| ENSG00000134873 | CLDN10 | −4.95 | 8.69E‐11 | 9.58E‐10 | |||||
| hsa‐miR‐204‐5p | hsa‐mir‐204 | −4.25 | 1.50E‐04 | 5.14E‐04 | ENSG00000113946 | CLDN16 | −25.37 | 5.29E‐10 | 4.48E‐09 |
| hsa‐miR‐204‐3p | hsa‐mir‐204 | −3.96 | 4.97E‐05 | 2.02E‐04 | ENSG00000164007 | CLDN19 | −26.79 | 8.10E‐13 | 2.00E‐11 |
| ENSG00000105329 | TGFB1 | 2.80 | 6.14E‐14 | 2.77E‐12 | |||||
| ENSG00000124216 | SNAIL1 | 1.78 | 1.21E‐03 | 2.33E‐03 | |||||
| hsa‐miR‐138‐5p | hsa‐mir‐138‐2 | −12.09 | 2.01E‐05 | 9.40E‐05 | ENSG00000039068 | CDH1 | −2.38 | 3.53E‐07 | 1.40E‐06 |
| hsa‐miR‐138‐5p | hsa‐mir‐138‐1 | −12.01 | 1.78E‐05 | 8.72E‐05 | |||||
| hsa‐miR‐9‐5p | hsa‐mir‐9‐1 | −6.32 | 2.73E‐04 | 8.36E‐04 | |||||
| hsa‐miR‐10a‐5p | hsa‐mir‐10a | −3.77 | 1.12E‐06 | 1.05E‐05 | |||||
| hsa‐miR‐10a‐3p | hsa‐mir‐10a | −2.71 | 1.86E‐05 | 8.94E‐05 | |||||
| hsa‐miR‐335‐5p | hsa‐mir‐335 | −2.85 | 2.03E‐05 | 9.40E‐05 | |||||
Relevant microRNA in EMT. Expression changes of microRNAs and their target mRNAs in ccRCC compared with normal tissue.