Table 1.

Characteristics of included studies

Study author(s)	Rat strain and sex	Rat weight (g)	Number of control rats	Number of model rats	Anesthetic	Detection time after modeling(h)	Pathology assessment
Li et al., 2011)	Wistar male	150-200	8	8	Chloral hydrate	1	microcirculation + thrombus
Wang et al., 2011	SD male	350-450	10	10	Chloral hydrate	24	thrombus
Zhang et al., 2016	SD male	250-350	10	10	Chloral hydrate	24	thrombus
Shi et al., 2006	Wistar Half male half female	250-300	10	10	Chloral hydrate	24	thrombus
Bao et al., 2008	Wistar Half male half female	250-300	10	10	NA	72	thrombus
Deng et al., 2007	SD female	220-240	10	10	Chloral hydrate	20	HE staining
Wang et al., 2007	SD male	200-220	10	10	urethane	NA	thrombus
Guo et al., 2009	SD Half male half female	180-200	10	10	Chloral hydrate	12	Blood perfusion
Gao et al., 2013	Wistar Half male half female	230-270	10	10	urethane	12	thrombus
Si et al., 2007	SD NA	280-300	8	8	pentobarbital	12	thrombus
Yin et al., 2008	SD Half male half female	280-320	8	8	pentobarbital	12	thrombus
Li et al., 2010	Wistar Half male half female	250-300	10	10	Chloral hydrate	12	thrombus
Peng et al., 2012	SD Half male half female	220-280	8	8	NA	12	microcirculation
Guo et al., 2012	SD Half male half female	180-200	10	10	Chloral hydrate	12	thrombus
Xie et al., 1999	SD male	230-260	10	10	NA	NA	thrombus
Chen et al., 2012	SD Half male half female	248-288	10	10	urethane	24	thrombus
Zhang et al., 2014	SD Half male half female	200-220	12	12	pentobarbital	24	thrombus
Li et al., 2001	SD male	120-160	10	10	NA	24	microcirculation

Note: NA = not available