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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Nat Struct Mol Biol. 2016 Dec 12;24(1):40–46. doi: 10.1038/nsmb.3336

Figure 5. Model of RAD51-mediated DNA strand exchange with depiction of the intermediate state.

Figure 5

(a) The interaction of RAD51 and three DNA strands in the intermediate state. The displaced strand is located in proximity to the C-terminal part of RAD51's potential secondary DNA binding site. The invading strand (red) and the complementary strand (blue) are stabilized by V273 and R235, respectively. (b) Interaction of R235 with the complementary strand and the various stretch ratios in different length of DNA compared to the B-form DNA. (c) A hypothetical model of DNA molecule transition during the synaptic reaction.