Table 4.
Number of mice with deficit* | Per cent of mice with deficit | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Score | 0 | 0.25 | 0.5 | 0.75 | 1 | 0 | 0.25 | 0.5 | 0.75 | 1 |
Temperature | 32 | 19 | 0 | 0 | 0 | 62.7 | 37.3 | 0.0 | 0.0 | 0.0 |
Body weight | 11 | 31 | 8 | 1 | 0 | 21.6 | 60.8 | 15.7 | 2.0 | 0.0 |
Score | 0 | 0.5 | 1 | 0 | 0.5 | 1 | ||||
Alopecia | 16 | 26 | 9 | 31.4 | 51.0 | 17.6 | ||||
Loss of fur colour | 9 | 32 | 10 | 17.6 | 62.7 | 19.6 | ||||
Dermatitis | 29 | 9 | 13 | 56.9 | 17.6 | 25.5 | ||||
Loss of whiskers | 41 | 4 | 6 | 80.4 | 7.8 | 11.8 | ||||
Coat condition | 8 | 27 | 16 | 15.7 | 52.9 | 31.4 | ||||
Tumours | 25 | 24 | 2 | 49.0 | 47.1 | 3.9 | ||||
Distended abdomen | 9 | 14 | 28 | 17.6 | 27.5 | 54.9 | ||||
Kyphosis | 3 | 12 | 36 | 5.9 | 23.5 | 70.6 | ||||
Tail stiffening | 27 | 20 | 4 | 52.9 | 39.2 | 7.8 | ||||
Gait disorders | 3 | 27 | 21 | 5.9 | 52.9 | 41.2 | ||||
Tremor | 16 | 21 | 14 | 31.4 | 41.2 | 27.5 | ||||
Forelimb grip strength | 3 | 35 | 13 | 5.9 | 68.6 | 25.5 | ||||
Body condition score | 1 | 17 | 33 | 2.0 | 33.3 | 64.7 | ||||
Vestibular disturbance | 26 | 23 | 2 | 51.0 | 45.1 | 3.9 | ||||
Hearing loss | 3 | 7 | 41 | 5.9 | 13.7 | 80.4 | ||||
Cataracts | 50 | 1 | 0 | 98.0 | 2.0 | 0.0 | ||||
Corneal capacity | 47 | 3 | 1 | 92.2 | 5.9 | 2.0 | ||||
Eye discharge/swelling | 38 | 10 | 3 | 74.5 | 19.6 | 5.9 | ||||
Microphthalmia | 45 | 6 | 0 | 88.2 | 11.8 | 0.0 | ||||
Vision loss | 1 | 16 | 34 | 2.0 | 31.4 | 66.7 | ||||
Menace reflex | 2 | 3 | 46 | 3.9 | 5.9 | 90.2 | ||||
Nasal discharge | 47 | 4 | 0 | 92.2 | 7.8 | 0.0 | ||||
Malocclusions | 47 | 4 | 0 | 92.2 | 7.8 | 0.0 | ||||
Rectal prolapse | 50 | 1 | 0 | 98.0 | 2.0 | 0.0 | ||||
Penile/uterine prolapse | 50 | 1 | 0 | 98.0 | 2.0 | 0.0 | ||||
Diarrhoea | 51 | 0 | 0 | 100 | 0.0 | 0.0 | ||||
Breathing rate/depth | 17 | 28 | 6 | 33.3 | 54.9 | 11.8 | ||||
Mouse grimace scale | 36 | 15 | 0 | 70.6 | 29.4 | 0.0 | ||||
Piloerection | 0 | 0 | 51 | 0.0 | 0.0 | 100 |
*Individual deficits used to create FI scores for 51 aged mice.