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CRMP treatment reduced hepatic triglyceride and DAG content but did not alter hepatic ceramide content. A) Liver triglyceride (TAG) content and liver histology. Scale bars, 100 μm. B) Plasma TAG content. C, D) Liver cytosol (C) and membrane (D) DAG content. E) Liver ceramide content. F) PKC-ε translocation in liver. Data are represented as means ± sem (n = 8 per group). Statistical significance determined by Student’s t test.
