Figure 2.
Treatment algorithm for confirmed periprosthetic infection, based on guideline recommendations
*1Standard procedure is to switch to oral administration after 2 weeks if clinical response is good (wound dry/normal, pain decreasing) and C-reactive protein (CRP) is normal; 4 weeks‘ IV antibiotic treatment if wound is not healing correctly/CRP remains high.
*2DTT: Difficult-to-treat pathogen: small-colony variant staphylococci, enterococci, quinolone-resistant Pseudomonas aeruginosa, all multiresistant pathogens/rifampicin resistance, pathogens with no orally bioavailable antibiotic
IV: Intravenous; SR: Sample removal; p.o.: Per os