Table 3.
Multivariate stepwise Cox regression analysis with Hazard ratio
| p-value | HR (95% CI) | |
|---|---|---|
| Antibiotic regime | ||
| Other antibiotic therapy | ||
| Moxifloxacin monotherapy | 0.86 | |
| Moxifloxacin combination-therapy | 0.99 | |
| Sex | 0.653 | |
| Age | 0.029 | 1.03 (1.00–1.05) |
| BMI | 0.042 | 0.95 (0.90–1.00) |
| History of prior pulmonary disease | 0.481 | |
| History of prior cardiovascular disease | 0.027 | 2.12 (1.06–4.35) |
| ECMO-Therapy | 0.222 | |
| Dialysis | 0.005 | 2.48 (1.31–4.71) |
| Horowitz-Index upon ICU admission | 0.987 | |
| SAPS-II | 0.313 | |
| LIS | 0.477 | |
| SOFA-Score | 0.358 | |
HR hazard ratio (specified in case of significant p-value of multivariate stepwise Cox regression analysis), CI confidence interval, BMI body-mass-index, ECMO extracorporeal membrane Oxygenation, SPAS: simplified acute physiology score, LIS Lung-Injury-Score, SOFA Sepsis-related organ failure assessment; Horowitz-Index: pO2/FiO2