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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Immunol. 2017 May 3;198(11):4413–4424. doi: 10.4049/jimmunol.1601991

Figure 1. The impact of concurrent targeted disruption of CD4 and CD8 genes on T cell development in the thymus in HLA-DR3 transgenic mice.

Figure 1

Thymocytes extracted from 3-week-old WT and DKO HLA-DR3 mice of either sex were enumerated and analyzed by flow cytometry following staining with indicated antibodies. Panel A represents total thymocyte count and panel B depicts distribution of various thymocyte subsets in thymus. Each bar represents mean±SE values from 6-8 mice/group. * p<0.05 and NS – Not significant.