Table 2.

LV volumes, EF and diastolic parameters evaluated by echocardiography in 80 healthy individuals, 100 HCM LVH− patients and 180 HCM LVH+ patients

	Healthy individuals (n=80)	HCM LVH− patients (n=100)	HCM LVH+ patients (n=180)	p Value
EDV/BSA (mL/m2)	57±14	49±13*	41±14*†	<0.001
ESV/BSA (mL/m2)	23±9	19±6*	16±7*†	<0.001
EF (%)	61±6	60±5	61±7	0.43
GLS (%)	−22.3±3.7	−21.3±2.4	−16.4±3.7*†	<0.001
E (m/s)	0.7±0.2	0.8±0.2	0.8±0.8	0.24
E/A ratio	1.4±0.5	1.6±0.6	1.3±0.7†	0.04
Deceleration time (ms)	195±48	175±30	217±74*†	<0.001
E/e′	6.4±2.1	7.0±2.2	14.9±8.3*†	<0.001
e′ (m/s)	0.12±0.03	0.06±0.03*	0.11±0.04*†	<0.001
LA area (cm2)	17.0±4.1	16.3±4.5	24.9±11.3*†	<0.001

The values are represented as mean±SD.

p values are based on Student’s t-test.

*p<0.05 compared with healthy individuals.

†p<0.05 compared with HCM LVH− patients.

A, atrial transmitral filling velocity; BSA, body surface area; e′, early diastolic myocardial velocity; E, early transmitral flow velocity; EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; GLS, global longitudinal strain; HCM, hypertrophic cardiomyopathy; HCM LVH−, HCM patients without increased wall thickness; HCM LVH+, HCM patients with increased wall thickness; LA, left atrium; LV, left ventricle; LVH, left ventricular hypertrophy.