- History of childhood head/neck irradiation [113] |
- Total body irradiation for bone marrow transplantation [114] |
- Exposure to ionizing radiation from fallout in childhood or adolescence [115, 116] |
- Family history of PTC, MTC, or thyroid cancer syndrome (e.g., Cowden’s syndrome, familial polyposis, Carney complex, multiple endocrine neoplasia [MEN] 2, Werner syndrome) [117] |
- Enlarging nodule/rapid nodule growth |
- Cervical lymphadenopathy |
- Fixed nodule to surrounding tissue |
- Vocal cord paralysis/hoarseness |