Table 1.
DTI-GWAS Task List. Our ENIGMA-Viewer is designed for these analytical tasks
| Index | Task | Example questions |
|---|---|---|
| 1 | Viewing distribution, | What is the most affected brain region under a certain disorder? |
| consistency, or | What is the overall data distribution of the effect size in all studies? | |
| inconsistency | Are the results consistent or very different? | |
| 2 | Detect trends | What is the distribution of cortical thicknesses and FA values? |
| How does effect size vary among studies? | ||
| 3 | Find association | What are the disorder (brain regions) and genetics correlates to risk? |
| How does brain structural change associated with | ||
| behavioral risks and changes and vulnerability? | ||
| How do geographical factors affect disease expression in the brain? | ||
| 4 | Locate extremes | What are the significant brain regions mostly affected by diseases? |
| 5 | Find local relationships | What are the differences between studies in terms of their effect size? |
| 6 | Compare different disorders | What are the common and different effects in the brain networks |
| between or among multiple disorders? | ||
| 7 | Compare disorders by regions | What are the regions affected or unique to a certain disorder? |