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. 2015 Dec 18;1:18. doi: 10.1186/s40842-015-0018-0

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© Holmes et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Reproduced with permission from Munson et al [21]. Association diagram showing the clinical milieu in which CN (pink node in center of square) often exists. Each node represents an ICD-9 code, with the size of the node proportional to its frequency in the overall dataset, and node colors representing high-level clinical categories (see legend). Edges between nodes represent highly significant associations. Arrowheads show temporality with preceding nodes pointing to subsequent nodes. This figure was made using the following criteria: Association p-value < 1.0 × 10^-176; association odds ratio > 200; temporal p-value < 1.0 x 10^-6. The two red nodes directly pointing to Charcot foot are related to type 2 diabetes (ICD-9 codes 250.60 and 250.90)