TABLE 2.
GyrA substitutiona | No. of isolatesb
|
||||||||
---|---|---|---|---|---|---|---|---|---|
Flock 1, Nalr Cipr | Flock 3
|
Flock 4
|
Flock 5
|
Flock 6, Nalr Cipr | Total | ||||
Nalr Cipr | Nalr Cips | Nalr Cipr | Nalr Cips | NALr Cipr | Qs | ||||
Ile-86 | 72 | 40 | 0 | 40 | 1 | 65 | 0 | 51 | 269 |
Ala-86 | 1 | 1 | 12 | 0 | 0 | 1 | 0 | 2 | 17 |
Asn-90 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 8 | 10 |
Ile-60 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Ile-86, Thr-86→Ile; Ala-86, Thr-86→Ala; Asn-90, Asp-90→Asn; Ile-60, Val-60→Ile.
Nalr Cipr, resistant to nalidixic acid (MICs ≥ 32 μg/ml) and ciprofloxacin (MICs ≥ 2 μg/ml); Nalr Cips, nalidixic acid resistant (MICs ≥ 32 μg/ml) and ciprofloxacin sensitive (MICs ≤ 1 μg/ml); Qs, quinolone sensitive.