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. Author manuscript; available in PMC: 2017 Jun 15.
Published in final edited form as: Mol Pharmacol. 1997 Sep;52(3):491–498. doi: 10.1124/mol.52.3.491

Fig. 2.

Fig. 2

Effects of p- and m-DITC-ADAC on inhibition of (−)-isoproterenol-stimulated cAMP accumulation in DDT cells. Intact DDT cells were incubated with 1 μM (−)-isoproterenol, 50 μM rolipram, and the indicated concentrations of CPA or p- or m- DITC-ADAC for 10 min at 37°. At the end of the incubation, the cAMP accumulated was determined as described in Experimental Procedures. Values are the mean ± standard error of four separate experiments, each performed in duplicate. The basal cAMP was 5.0 ± 1.7 pmol/mg of protein/min, and the cAMP accumulated in the presence of 5 μM (−)-isoproterenol alone was 60.0 ± 9.0 pmol/mg of protein/min.