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. 2017 Jan 26;43(4):891–899. doi: 10.1093/schbul/sbw173

Fig. 1.

Fig. 1.

Decreased isoform-specific postsynaptic density-95 (PSD-95) mRNA expression in the dorsolateral prefrontal cortex (DLPFC) in schizophrenia. Quantitative PCR analysis of mRNA isolated from control (ctl, N = 210) and schizophrenia (scz, N = 175) subjects revealed decreased isoform-specific expression in the DLPFC in schizophrenia. No change was found with an assay that detected both alpha (α) and truncated (trunc) isoforms, while schizophrenia samples had decreased beta (β) (t = 4.7, df = 346.7, P < .05) and truncated isoform expression (t = 3.5, df = 373.5, P < .05). *P < .05.